Evergreen Therapeutics Inc. announced on September 23, 2020 eastern time that the FDA has officially approved the company's phase I clinical application for the COVID-19 oral capsule EG-009. The IND application was submitted under the FDA's CTAP* program specific to the Novel Coronavirus Pneumonia. The entire IND review took only 26 natural days. EG-009 is one of nine research and development pipelines of EG-009 for the treatment of cytokine storms caused by COVID-19. Cytokine storm is one of the main causes of death in COVID-19 patients. The oral drug EG-009 is used mainly to prevent and treat the cytokine storm caused by the novel Coronavirus (Cytokine release syndrome). At a time when the global COVID-19 pandemic continues, the development of EG-009 will bring new

In July 2020, Evergreen Therapeutics, Inc. announced its partnership with a leading U.S. laboratory to conduct animal experiment on the effectiveness of PR2005 in treating cytokine storms caused by COVID-19. This trial will provide further evidence of the effectiveness of PR2005 in the treatment of COVID-19.  The laboratory is an independent, non-profit biomedical research institution dedicated to contributing to better health care in the future. Based on each person's unique genetic makeup, the laboratory will discover accurate disease genome solutions, and entrust the global biomedical community with a common mission – to improve human health. The laboratory is a cancer center designated by the National Cancer Institute that hosts the NIH research center on a

In April 2020, Evergreen Therapeutics, Inc. announced the development of a new pipeline, EG-009, to treat the Cytokine Release Syndrome (CRS) caused by the Novel Coronavirus pneumonia. Epidemiologists predict that the world will remain in a pandemic state until June 2021. The virus continues to spread at a slow rate, and intermittent lockdowns are the new normal. It is estimated that 250 million people worldwide will be infected and 1.75 million will die by June 2021.CRS is one of the leading causes of death in COVID-19 patients. CRS is a complex inflammatory response. During the occurrence of CRS, various cytokines such as TNF-, IL-1, IL-6, IL-12, IFN-, IFN-, McP-1, and IL-8 are produced in large quantities in body fluids. CRS can cause acute respiratory distress syndrome and mu

On January 1st, 2020, Dr. Xin Du, former FDA senior reviewer, joined Evergreen Therapeutics Inc. as CEO to comprehensively lead the company's R&D. Dr. Du is a drug R&D expert with more than 20 years of biomedical background, and has a rich combination experience of FDA and industry in drug registration and drug development. Heis familiar with FDA and global regulations on drug development, production, quality management, clinical design and testing. At the same time, he has rich experience in drug R&D, and used to workin multiple multinational and Chinese pharmaceutical companies.Dr. Du Xin was a CMC reviewer in FDA and responsible for reviewing INDs and BLAs of biopharmaceuticals. After that he worked in multinational corporation at Aventis-Pastuer/Sanofi, Wyeth/Pfizer, Novartis,

On September 5th, 2019, Dr. Tao Du, the chairman of Evergreen Therapeutics Inc. , went to the famous Meakins-Christie Laboratories (MCL) of McGill University of Canada, known as the most prestigious respiratory disease institute in the world, for academic exchange activities with his team. Dr. Tao Du and team members discussed collaboration in respiratory disease research with Professor James G Martin, former director of MCL and current leader of internal medicine at McGill University School of Medicine. Both determined that research will be carried out in the fields of respiratory rare diseases and asthma and agreed to have in depth cooperation in clinical trials of respiratory rare diseases.Professor James G Martin has 35 years of clinical and scientific experience in the field